Vice President/Chief Nursing Officer
Penn Presbyterian Medical Center

Nicole Hoke, DNP, RN, CCRN, CCNS, serves as chief nursing officer and vice president at Penn Presbyterian Medical Center within the University of Pennsylvania Health System. Since joining Penn Medicine in 2008, she has led teams across diverse clinical settings with a focus on innovation, quality, and professional excellence. Prior to her current role, Hoke served as associate chief nursing officer at the Hospital of the University of Pennsylvania, where she spearheaded major strategic initiatives and service expansions. She began her Penn Medicine career as a clinical nurse in the neuro-trauma surgical ICU and later became one of the nation’s first perioperative clinical nurse specialists. A recognized expert and national presenter, she has authored multiple peer-reviewed publications and received honors including the Victoria Rich Transformation Award. She earned a Master of Science in Nursing from Widener University in 2009 and a Doctor of Nursing Practice in Leadership and Innovation from the University of Missouri in 2023. She holds national certifications as a critical care registered nurse and adult clinical nurse specialist and is passionate about advancing the nursing profession, mentoring emerging leaders, and driving excellence in patient care.